Pain Relief: Wild lettuce is sometimes referred to as "opium lettuce" due to its potential analgesic properties. It contains compounds like lactucopicrin and lactucin, which may help alleviate pain, making it a natural alternative for mild to moderate pain relief.

Sedative and Relaxant: Wild lettuce has been traditionally used as a natural sedative to promote relaxation and improve sleep. It can help reduce anxiety, tension, and restlessness, making it beneficial for people who have trouble sleeping or suffer from insomnia.

Cough Suppressant: Wild lettuce has mild antitussive (cough-suppressing) properties. It has been used to calm persistent coughs, particularly those associated with bronchitis or asthma.

Anti-Inflammatory Properties: The plant contains compounds that may help reduce inflammation. This makes it potentially useful for conditions characterized by inflammation, such as arthritis or other inflammatory disorders.

Migraine Relief: Some people use wild lettuce tincture to help alleviate migraines and headaches. Its potential pain-relieving and sedative effects may contribute to its efficacy in managing headache symptoms

Wild lettuce is used for whooping cough, asthma, urinary tract problems, cough, trouble sleeping (insomnia), restlessness, excitability in children, painful menstrual periods, excessive sex drive in women (nymphomania), muscular or joint pains, poor circulation, and swollen genitals in men (priapism).